γδ TCR repertoires
During this process, the variable (V) domain, the diversity (D) domain, and the joining (J) domains of somatic DNA recombine and create the diversity of γδ TCR chains. As a result, all γδ T cells are merged to form large γδ TCR repertoires. Moreover, pilot studies have indicated that the composition of specific γδ TCR repertoires is associated with the disease development in the human body. However, only a few TCR ligands, proteins, or factors have been confirmed that can be used for promoting the γδ TCR repertoire and activation.
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