Site-specific Recombination
Site-specific recombination is a type of genetic recombination in which DNA strand exchange takes place between segments possessing at least a certain degree of sequence homology. Site-specific Recombination (SSR) perform rearrangements of DNA segments by recognizing and binding to short DNA sequences (sites), at which they cleave the DNA backbone, exchange the two DNA helices involved and rejoin the DNA strands. Site-specific DNA recombination requires both a recombinase protein and a pair of repeated DNA sites at which recombination takes place.
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