Target-Based Peptidomimetic Development Service
Introduction to Target-Based Peptidomimetic Development
An in-depth understanding of the function and pathology of cells provides many potential targets for the development of new therapeutic and diagnostic agents. However, a general problem with translating this knowledge into therapeutics is that these targets are functionally incapable of drug development. Screening methods similar to mRNA display and phage display have been shown to generate peptidomimetics capable of binding to and modulating PPI for the study of a wide range of protein interactions. Undoubtedly, the identification and better understanding of the interaction between peptidomimetics and their therapeutic targets has dramatically changed the paradigm of drug discovery.
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