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Winning Position: Unresolved
Relying on the technology platform of the tumor microenvironment center, Alfa Oncology provides a full range of molecular biology services for tumor microenvironment (TME) research to help researchers successfully achieve their research goals.Introduction of tumor multi-omics servicesTumor is a complex polygenic disease, and it is difficult to explain the entire pathogenesis of tumors with the characteristics of a single gene. To explore the change rules of genes from the perspective of polygenes is a key entry point for the current study of tumor pathogenesis. Tumor molecular biology takes the study of important tumor-related genes as an entry point to reveal the molecular mechanisms and cell signaling pathways of the occurrence and development of malignant tumors, and then proposes new targets and strategies for gene diagnosis and gene therapy, and explores new ways of tumor prevention and treatment.
Winning Position: Unresolved
Brain tumor drug target identification and validationAlfa Oncology identifies promising targets in early drug discovery. We develop and implement high-throughput target ID screens that characterize a wide range of analytes from small molecular fragments to biologics. We utilize non-labeled binding technologies such as bio-layer interference (BLI) and surface plasmon resonance (SPR) systems to rapidly establish high-throughput binding screens. Our services can be used to identify binding targets and accurately characterize complex formation rates, complex stability, and affinity.
Winning Position: Unresolved
Relying on the tumor microenvironment center technology platform, Alfa Oncology provides custom services for 3D tumor cell models for TME studies, helping researchers successfully achieve their research goals.Introduction of 3d cell cultureTumors involve cellular alterations, including growth and division that take cells out of their normal limits, leading to invasion and destruction of adjacent tissues and eventual metastasis to distant sites in the body. Oncology researchers need better research tools that allow them to more easily study the complex, unknown interactions between tumor cells and their environment and identify points of therapeutic intervention for tumors.
Winning Position: Unresolved
Gene methylation, gene mutations, and protein markers are commonly used biomarkers for brain tumor diagnosis. However, the mechanisms of brain tumorigenesis are complex, and a large number of studies have demonstrated the limitations of relying on single omics, as the analysis of single-level data can only provide little cause-and-effect relationships. In contrast, a multi omics data integration strategy spanning genomic, transcriptomic, proteomic, and metabolomic levels of different cellular functions has the potential to provide unparalleled insights into the underlying biology of brain tumors.Learn more:omics services for brain tumors
Winning Position: Unresolved
Relying on the technology platform of the tumor microenvironment center, Alfa Oncology provides a full range of sequencing and analysis services of single-cell omics and spatial omics for TME research to help researchers successfully achieve their research goals.IntroductionWith the development of life science and technology, multi-omics studies based on single-cell resolution and spatial location are rapidly applied in the tumor microenvironment.Alfa Oncology has established a well-established tumor microenvironment central technology platform with an experienced team of experts and mature technologies, aiming to provide our global customers with efficient and validated tumor models for tumor and microenvironment research and Anticancer drug discovery. Among them, the single-cell multi-omics platform combines spatial omics technology to study the tumor microenvironment from multiple levels, multiple perspectives, and multiple omics. It can simultaneously learn information such as intercellular connections, gene spatial changes, cell distribution and tissue distribution of key genes, and even spatio-temporal dynamic distribution changes, so as to more accurately study the heterogeneity of tumors and their microenvironment, and how the tumor microenvironment plays a role in tumors. relevant molecular mechanisms of action in the process and explore potential therapeutic targets.Learn more:single-cell omics of tme